seroprevalence of hepatitis a in hemodialysis patient candidate for kidney transplant younger than forty years

نویسندگان

sara abolghasemi infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, iran

shahnaz sali infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, iran

ensieh arabsaghari infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, iran

yasan sadeghian infectious diseases and tropical medicine research center, shahid beheshti university of medical sciences, tehran, iran

چکیده

introduction: worldwide, hepatitis a is a common infection during childhood especially in developing countries. it can cause severe complications in immunocompromised patients, including kidney transplants patients and chronic liver disease. due to the increasing number of kidney transplants in the country and epidemiologic shift of hav which was observed in previous studies, we're going to review the epidemiology of hepatitis a in hemodialysis patients less than forty years serving kidney transplant candidates to follow vaccination policy for them. methods: in a cross sectional study during 1393-1394 hepatitis a antibody levels in hemodialysis patients less than forty years of kidney transplant candidates examined in 12 hospitals in tehran, iran. their serums were tested for anti hav igm & igg by elisa kits. results: hepatitis a virus antibody was positive in 66 (72.5%) of 91 patients. the prevalence of hav was 0 % at the range of younger than 20 and 45% in under 25 years age group. this significantly increased prevalence by increasing the age, and there was according to epidemiological shifts which were shown in other studies. discussion: due to the availability of vaccine and hepatitis severe complications in immunocompromised individuals, as well as a low prevalence of positive serology in individuals under 25 years, it seems check of antibodies in patients undergoing kidney transplantation and vaccination in seronegative persons is a logical. keywords: dialysis patients; hepatitis a; seroprevalence

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عنوان ژورنال:
novelty in biomedicine

جلد ۲۰۱۷، شماره ۰۳، صفحات ۰-۰

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